Asymmetric preparation of antifungal 1-(4 -chlorophenyl)-1-cyclopropyl methanol and 1-(4 -chlorophenyl)-2-phenylethanol. Study of the detoxification mechanism by Botrytis cinerea

Identificadores
URI: http://hdl.handle.net/10498/17362
DOI: 10.1016/j.molcatb.2011.02.005
ISSN: 1381-1177
Statistics
Metrics and citations
Share
Metadata
Show full item recordDate
2011-02-24Department
Química OrgánicaSource
Journal of Molecular Catalysis B: Enzymatic, 2011, vol. 70, pp. 61–66Abstract
Chiral alcohols are important as bioactive compounds or as precursors to such molecules. On the basis of
the different antifungal properties of the enantiopure alcohol derivatives of 4-chlorophenyl cyclopropyl
ketone and benzyl 4-chlorophenyl ketone, their enantioselective synthesis by chemical and biocatalytic
methods was studied. The detoxification pathways by the phytopathogen fungus Botrytis cinerea are
reported.
Subjects
Asymmetric preparation; Botrytis cinerea; Lipase; Baker’s yeast; 1-(4 -Chlorophenyl)-1-cyclopropyl; 1-(4 -Chlorophenyl)-2-phenylethanolCollections
- Artículos Científicos [4817]
- Artículos Científicos INBIO [264]
- Artículos Científicos IVAGRO [289]
- Articulos Científicos Quim. Org. [174]