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dc.contributor.authorF. García, Benito
dc.contributor.authorTorres Martínez, Ascensión 
dc.contributor.authorMacías Domínguez, Francisco Antonio 
dc.contributor.otherQuímica Orgánicaen_US
dc.date.accessioned2018-04-10T07:05:16Z
dc.date.available2018-04-10T07:05:16Z
dc.date.issued2015-11
dc.identifier.urihttp://hdl.handle.net/10498/20320
dc.description.abstractThe citrus by-products released from citrus processing plants may contain high levels of potentially bioactive compounds such as flavonoids, which are a widely distributed group of polyphenolic compounds with health-related properties based on their antioxidant activity. In the study reported here, the potential bioactivities and antioxidant activities of extracts, fractions and compounds from citrus by-products were evaluated along with the chemical interactions of binary mixtures of compounds and complex mixtures. The bioactivities and interactions were evaluated in wheat coleoptile bioassays and the antioxidant activity was evaluated by the al DPPH (2,2-diphenyl-1-picrylhdrazyl radical) radical scavenging assay. The extracts, fractions and most of the isolated compounds (mainly polymethoxyflavones) showed high activity in the wheat coleoptile bioassay. However, the antioxidant activity was not consistently high, except in the acetone extract fractions. Moreover, a study of the interactions with binary mixtures of polymethoxyflavones showed the occurrence of synergistic effects. The complex mixtures of fractions composed mainly of polymethoxyflavones caused a synergistic effect when it was added to a bioactive compound such as anethole. The results reported here highlight a new application for the wheat coleoptile bioassay as a quick tool to detect potential synergistic effects in compounds or mixtures.en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.publisherMoleculesen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceMolecules 2015, 20, 20079–20106en_US
dc.subjectcitrus by-productsen_US
dc.subjectFlavonoidsen_US
dc.subjectsynergismen_US
dc.subjectisobolographyen_US
dc.subjectDPPHen_US
dc.subjectcoleoptilesen_US
dc.titleSynergy and Other Interactions between Polymethoxyflavones from Citrus Byproductsen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.rights.accessRightsinfo:eu-repo/semantics/openAccessen_US
dc.identifier.doi10.3390/molecules201119677


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This work is under a Creative Commons License Attribution-NonCommercial-NoDerivatives 4.0 Internacional