Allylic Oxidation of Alkenes Catalyzed by a Copper−Aluminum Mixed Oxide

Statistics
Metrics and citations
Share
Metadata
Show full item recordDate
2014-03Department
Química OrgánicaSource
Organic Letters 2014, 16, 1598−1601Abstract
A strategy for the allylic oxidation of cyclic alkenes with a copper−aluminum mixed oxide as catalyst is presented. The reaction involves the treatment of an alkene with a carboxylic acid employing tert-butyl hydroperoxide as the oxidant. In all cases, the corresponding allylic esters are obtained. When L-proline is employed, the allylic alcohol or ketone is obtained. The oxidation of cyclohexene and valencene has been optimized by design of experiments (DoE) statistical methodology.
Subjects
allylic oxidationCollections
- Artículos Científicos [4980]
- Artículos Científicos INBIO [269]
- Articulos Científicos Quim. Org. [180]