Hydrolysable Tannins and Biological Activities of Meriania hernandoi and Meriania nobilis (Melastomataceae)

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URI: http://hdl.handle.net/10498/21259

DOI: 10.3390/molecules24040746

ISSN: 1420-3049

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Author/s
Valverde Malaver, Claudia Lorena; Colmenares Dulcey, Ana Julia; Rial Cumbrera, CarlosAuthority UCA; Varela Montoya, Rosa MaríaAuthority UCA; González Molinillo, José MaríaAuthority UCA; Macías Domínguez, Francisco AntonioAuthority UCA
Date
2019-02
Department
Química Orgánica
Source
Molecules 2019, 24, 746
Abstract
A bio-guided study of leaf extracts allowed the isolation of two new macrobicyclic hydrolysable tannins, namely merianin A (1) and merianin B (2), and oct-1-en-3-yl b-xylopyranosyl-(1”-6’)-b-glucopyranoside (3) from Meriania hernandoi, in addition to 11 known compounds reported for the first time in the Meriania genus. The structures were elucidated by spectroscopic analyses including one- and two-dimensional NMR techniques and mass spectrometry. The bioactivities of the compounds were determined by measuring the DPPH radical scavenging activity and by carrying out antioxidant power assays (FRAP), etiolated wheat coleoptile assays and phytotoxicity assays on the standard target species Lycopersicum esculentum W. (tomato). Compounds 1 and 2 exhibited the best free radical scavenging activities, with FRS50 values of 2.0 and 1.9 M, respectively.
Subjects
Melastomataceae; Meriania; M. hernandoi; M. nobilis; polyphenols; hydrolysable tannins; DPPH; FRAP; phytotoxicity
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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This work is under a Creative Commons License Attribution-NonCommercial-NoDerivatives 4.0 Internacional