Hydrolysable Tannins and Biological Activities of Meriania hernandoi and Meriania nobilis (Melastomataceae)

Identificadores
URI: http://hdl.handle.net/10498/21259
DOI: 10.3390/molecules24040746
ISSN: 1420-3049
Files
Statistics
Metrics and citations
Share
Metadata
Show full item recordDate
2019-02Department
Química OrgánicaSource
Molecules 2019, 24, 746Abstract
A bio-guided study of leaf extracts allowed the isolation of two new macrobicyclic
hydrolysable tannins, namely merianin A (1) and merianin B (2), and oct-1-en-3-yl
b-xylopyranosyl-(1”-6’)-b-glucopyranoside (3) from Meriania hernandoi, in addition to 11 known
compounds reported for the first time in the Meriania genus. The structures were elucidated by
spectroscopic analyses including one- and two-dimensional NMR techniques and mass spectrometry.
The bioactivities of the compounds were determined by measuring the DPPH radical scavenging
activity and by carrying out antioxidant power assays (FRAP), etiolated wheat coleoptile assays
and phytotoxicity assays on the standard target species Lycopersicum esculentum W. (tomato).
Compounds 1 and 2 exhibited the best free radical scavenging activities, with FRS50 values of
2.0 and 1.9 M, respectively.
Subjects
Melastomataceae; Meriania; M. hernandoi; M. nobilis; polyphenols; hydrolysable tannins; DPPH; FRAP; phytotoxicityCollections
- Artículos Científicos [4980]
- Artículos Científicos INBIO [269]
- Articulos Científicos Quim. Org. [180]