Brain Structural and Functional Changes in Cognitive Impairment Due to Alzheimer's Disease

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URI: http://hdl.handle.net/10498/27537
DOI: 10.3389/fpsyg.2022.886619
ISSN: 1664-1078
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2022-06Department
PsicologíaSource
Frontiers in Psychology, Vol. 13Abstract
Cognitive neuropsychology seeks a potential alignment between structural and
functional brain features to explain physiological or pathological processes, such as
Alzheimer’s disease (AD). Several structural and functional brain changes occurring
during the disease, including cognitive impairment, are found at the end of the patient’s
life, but we need to know more about what happens before its onset. In order to do
that, we need earlier biomarkers at preclinical stages, defined by those biomarkers,
to prevent the cognitive impairment. In this minireview, we have tried to describe the
structural and functional changes found at different stages during AD, focusing on those
features taking place before clinical diagnosis.
Subjects
structural changes; functional changes; early markers; reversion; cognitive impairment (CI)Collections
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