RT journal article T1 Adaptation profiles comprising objective and subjective measures in fibromyalgia: The al-Ándalus project A1 Estévez López, Fernando A1 Segura Jiménez, Víctor A1 Álvarez Gallardo, Inmaculada Concepción A1 Borges Cosic, Milkana A1 Pulido Martos, Manuel A1 Carbonell Baeza, Ana A1 Aparicio, Virginia Ariadna A1 Greenen, Rinie A1 Delgado Fernández, Manuel A2 Didáctica de la Educación FísicaPlástica y Musical K1 Accelerometry K1 Chronic pain K1 Cognitive performance K1 Coping K1 Epidemiology K1 Functional capacity K1 Patient subgroups K1 Quality of life K1 Resilience (psychological) K1 Vulnerability (psychological) AB Objectives. The aim of this study was to identify subgroups in terms of adaptation to FM and to test differences in FM severity between these subgroups. Methods. The al-Ándalus project made it possible to perform a comprehensive population-based crosssectional study in 486 FM patients including multiple assessments of modifiable (could be targeted in therapy) resilience and vulnerability factors, measured by objective and subjective assessments, related to psychological and physical function. FM severity was assessed by means of FM impact (total score of the Revised Fibromyalgia Impact Questionnaire) and distress (Polysymptomatic Distress Scale of the modified 2011 preliminary criteria for FM). Exploratory factor analysis, cluster analysis and analysis of variance were conducted. Results. Factor analysis yielded eight factors: three included objective measures (declarative memory, active lifestyle and objective physical fitness) and five included subjective measures (fatigue, psychological distress, catastrophizing, resilience and subjective physical fitness). Cluster analysis based on these eight factors identified five profiles: Adapted (16%), Fit (18%), Poor performer (20%), Positive (20%) and Maladapted (26%). Most profile comparisons revealed different levels of FM severity varying from Adapted (the most favourable profile) to Maladapted (the most unfavourable profile) with Fit, Poor performer and Positive obtaining intermediate positions. Conclusions. Heterogeneity of FM was shown by five clinically meaningful profiles of modifiable factors that were associated with FM severity. It is of clinical interest to examine whether these profiles are associated with FM prognosis and the effectiveness of interventions, which would enhance the development of customized interventions based on adaptation profiles in FM. PB Oxford University Press SN 1462-0324 YR 2017 FD 2017 LK http://hdl.handle.net/10498/30570 UL http://hdl.handle.net/10498/30570 LA eng NO We acknowledge Oxford University Press and Rheumatology for publishing our scientific article: Estévez-López, F., Segura-Jiménez, V., Álvarez-Gallardo, I. C., Borges-Cosic, M., Pulido-Martos, M., Carbonell-Baeza, A., Aparicio, V. A., Geenen, R., & Delgado-Fernández, M. (2017). Adaptation profiles comprising objective and subjective measures in fibromyalgia: The al-Ándalus project. Rheumatology (United Kingdom), 56(11), 2015-2024. https://doi.org/10.1093/RHEUMATOLOGY/KEX302 DS Repositorio Institucional de la Universidad de Cádiz RD 25-may-2026