@misc{10498/20578,
year = {2014},
month = {11},
url = {http://hdl.handle.net/10498/20578},
abstract = {The structure 3,4-dihydroxy-2,4,6,8-tetramethyldec-8-enolide (1) was assigned to a metabolite of Botrytis cinerea, but the spectra of several synthetic analogues had significant differences from that of 1. Examination of the constituents of a B. cinerea mutant that overproduces polyketides gave sufficient quantities of 1, now named cinbotolide, for chemical transformations. These led to a revised γ-butyrolactone structure for the metabolite. This structure has been confirmed by an asymmetric total synthesis, which also established its absolute configuration.},
publisher = {ACS Publications},
title = {The Asymmetric Total Synthesis of Cinbotolide: A Revision of the Original Structure},
doi = {10.1021/jo501471m},
author = {Botubol Ares, José Manuel and Durán Peña, María Jesús and Macías Sánchez, Antonio José and R. Hanson, James and González Collado, Isidro and Hernández Galán, Rosario},
}