@misc{10498/24512,
year = {2021},
month = {1},
url = {http://hdl.handle.net/10498/24512},
abstract = {Invasive fusariosis (IF) is associated with severe neutropenia in patients with concurrent hematologic conditions. We conducted a retrospective observational study to characterize the epidemiology of IF in 18 Spanish hospitals during 2000-2015. In that time, the frequency of IF in nonneutropenic patients increased from 0.08 cases per 100,000 admissions in 2000-2009 to 0.22 cases per 100,000 admissions in 2010-2015. Nonneutropenic IF patients often had nonhematologic conditions, such as chronic cardiac or lung disease, rheumatoid arthritis, history of solid organ transplantation, or localized fusariosis. The 90-day death rate among nonneutropenic patients (28.6%) and patients with resolved neutropenia (38.1%) was similar. However, the death rate among patients with persistent neutropenia (91.3%) was significantly higher. We used a multivariate Cox regression analysis to characterize risk factors for death: persistent neutropenia was the only risk factor for death, regardless of antifungal therapy.},
publisher = {CENTERS DISEASE CONTROL & PREVENTION},
title = {Invasive Fusariosis in Nonneutropenic Patients, Spain, 2000-2015},
doi = {10.3201/eid2701.190782},
author = {Pérez-Nadales, Elena and Alastruey-Izquierdo, Ana and Linares-Sicilia, María José and Soto-Debrán, Juan Carlos and Abdala, Edson and García-Rodríguez, Julio and Montejo, Miguel and Muñoz, Patricia and Salavert Lletí, Miguel and Rezusta, Antonio and Ruiz Pérez de Pipaón, Maite and Yáñez, Lucrecia and Merino, Esperanza and Campos-Herrero, María Isolina and Costa-Mateo, José María and Fortún, Jesús and García-Lozano, Tomás and Garcia-Vidal, Carolina and Fernández-Ruiz, Mario and Sánchez-Reus, Ferrán and Castro-Méndez, Carmen and Guerrero Lozano, Inmaculada and Soler-Palacín, Pere and Aguado, José María and Martínez-Martínez, Luis and Torre-Cisneros, Julian and Nucci, Marcio and Spanish Fusariosis Study Group},
}