@misc{10498/24932,
year = {2021},
month = {3},
url = {http://hdl.handle.net/10498/24932},
abstract = {Most countries affected by the COVID-19 pandemic have repeatedly restricted public life to control the contagion. However, the health impact of confinement measures is hitherto unclear. We performed a multinational survey investigating changes in mental and physical well-being (MWB/PWB) during the first wave of the pandemic. A total of 14,975 individuals from 14 countries provided valid responses. Compared to pre-restrictions, MWB, as measured by the WHO-5 questionnaire, decreased considerably during restrictions (68.1 +/- 16.9 to 51.9 +/- 21.0 points). Whereas 14.2% of the participants met the cutoff for depression screening pre-restrictions, this share tripled to 45.2% during restrictions. Factors associated with clinically relevant decreases in MWB were female sex (odds ratio/OR = 1.20, 95% CI: 1.11-1.29), high physical activity levels pre-restrictions (OR = 1.29, 95% CI 1.16-1.42), decreased vigorous physical activity during restrictions (OR = 1.14, 95% CI: 1.05-1.23), and working (partially) outside the home vs. working remotely (OR = 1.29, 95% CI: 1.16-1.44/OR = 1.35, 95% CI: 1.23-1.47). Reductions, although smaller, were also seen for PWB. Scores in the SF-36 bodily pain subscale decreased from 85.8 +/- 18.7% pre-restrictions to 81.3 +/- 21.9% during restrictions. Clinically relevant decrements of PWB were associated with female sex (OR = 1.62, 95% CI: 1.50-1.75), high levels of public life restrictions (OR = 1.26, 95% CI: 1.18-1.36), and young age (OR = 1.10, 95% CI: 1.03-1.19). Study findings suggest lockdowns instituted during the COVID-19 pandemic may have had substantial adverse public health effects. The development of interventions mitigating losses in MWB and PWB is, thus, paramount when preparing for forthcoming waves of COVID-19 or future public life restrictions.},
organization = {DJ-P is supported by a grant from the Spanish Ministry of Science and Innovation-MINECO (RYC-2014-16938). The research fellowship of KH was funded by the German Research Foundation (Grant no. HO 6214/2-1).},
publisher = {FRONTIERS MEDIA SA},
keywords = {coronavirus},
keywords = {WHO-5},
keywords = {SF-36},
keywords = {psychological health},
keywords = {pain},
keywords = {lockdowns},
title = {Drastic Reductions in Mental Well-Being Observed Globally During the COVID-19 Pandemic: Results From the ASAP Survey},
doi = {10.3389/fmed.2021.578959},
author = {Wilke, Jan and Hollander, Karsten and Mohr, Lisa and Edouard, Pascal and Fossati, Chiara and González-Gross, Marcela and Sánchez Ramírez, Celso and Laiño, Fernando and Tan, Benedict and Pillay, Julian David and Pigozzi, Fabio and Jiménez Pavón, David and Sattler, Matteo C. and Jaunig, Johannes and Zhang, Mandy and van Poppel, Mireille and Heidt, Christoph and Willwacher, Steffen and Vogt, Lutz and Verhagen, Evert and Hespanhol, Luiz and Tenforde, Adam S.},
}