@misc{10498/24977,
year = {2021},
month = {5},
url = {http://hdl.handle.net/10498/24977},
abstract = {Background Irritant contact dermatitis (ICD) is caused by the acute locally toxic effect of a strong irritant, or the cumulative exposure to various weaker physical and/or chemical irritants.

Objectives To describe the characteristics of patients with ICD in the population patch tested in the European Surveillance System on Contact Allergies (ESSCA; ) database.

Methods Data collected by the ESSCA in consecutively patch-tested patients from January 2009 to December 2018 were analyzed.

Results Of the 68 072 patients, 8702 were diagnosed with ICD (without concomitant allergic contact dermatitis [ACD]). Hand and face were the most reported anatomical sites, and 45.7% of the ICD was occupational ICD (OICD). The highest proportions of OICD were found in metal turners, bakers, pastry cooks, and confectionery makers. Among patients diagnosed with ICD, 45% were found sensitized with no relevance for the current disease.

Conclusions The hands were mainly involved in OICD also in the subgroup of patients with contact dermatitis, in whom relevant contact sensitization had been ruled out, emphasizing the need for limiting irritant exposures. However, in difficult-to-treat contact dermatitis, unrecognized contact allergy, or unrecognized clinical relevance of identified allergies owing to incomplete or wrong product ingredient information must always be considered.},
publisher = {WILEY},
keywords = {body site},
keywords = {eczema},
keywords = {epidemiology},
keywords = {irritant contact dermatitis},
keywords = {occupational contact dermatitis},
keywords = {patch testing},
keywords = {RRID},
keywords = {SCR_001905},
keywords = {sensitization},
title = {European Surveillance System on Contact Allergies (ESSCA): Characteristics of patients patch tested and diagnosed with irritant contact dermatitis},
doi = {10.1111/cod.13833},
author = {Loman, Laura and Uter, Wolfgang and Armario Hita, José Carlos and Ayala, Fabio and Balato, Anna and Ballmer-Weber, Barbara K. and Bauer, Andrea and Bircher, Andreas J. and Buhl, Timo and Czarnecka-Operacz, Magdalena and Dickel, Heinrich and Fuchs, Thomas and Giménez Arnau, Ana and John, Swen M. and Kränke, Birger and Kręcisz, Beata and Mahler, Vera and Rustemeyer, Thomas and Sadowska-Przytocka, Anna and Sánchez-Pérez, Javier and Scherer Hofmeier, Kathrin and Schliemann, Sibylle and Simon, Dagmar and Spiewak, Radoslaw and Spring, Philip and Valiukevicienė, Skaidra and Wagner, Nicola and Weisshaar, Elke and Pesonen, Maria and Schuttelaar, Marie L. A. and ESSCA Working Group},
}