@misc{10498/25039, year = {2021}, month = {5}, url = {http://hdl.handle.net/10498/25039}, abstract = {Annona cherimola Mill., or the custard apple, is one of the species belonging to the Annonaceae family, is widely used in traditional medicine, and has been reported to be a valuable source of bioactive compounds. A unique class of secondary metabolites derived from this family are Annonaceous acetogenins, lipophilic polyketides considered to be amongst the most potent antitumor compounds. This review provides an overview of the chemical diversity, isolation procedures, bioactivity, modes of application and synthetic derivatives of acetogenins from A. cherimola Mill.}, organization = {This work was financially supported by the 'Ministerio de Economia y Competitividad' (Project AGL2017-88083-R), Spain. F.J.R.M. thanks Universidad de Cadiz for predoctoral support under grant 2018-009/PU/EPIF-FPI-CT/CP.}, publisher = {MDPI}, keywords = {Annona cherimola}, keywords = {acetogenins}, keywords = {bioactivity}, keywords = {acetogenin encapsulation}, keywords = {acetogenin formulation}, keywords = {acetogenin drug delivery}, title = {An Overview of the Chemical Characteristics, Bioactivity and Achievements Regarding the Therapeutic Usage of Acetogenins from Annona cherimola Mill.}, doi = {10.3390/molecules26102926}, author = {García Durán, Alexandra and Gutiérrez Vázquez, María Teresa and Rodríguez Mejías, Francisco Javier and González Molinillo, José María and Macías Domínguez, Francisco Antonio}, }