@misc{10498/26619,
year = {2022},
month = {3},
url = {http://hdl.handle.net/10498/26619},
abstract = {Alterations in ambulatory blood pressure detected by monitoring (ABPM) have been associated with perinatal complications in hypertensive pregnant women. Aim: To establish the relationships between the blood pressure (BP) profiles detected by ABPM and adverse perinatal outcomes in normotensive women with gestational diabetes mellitus (GDM). Methods: A prospective study of normotensive women in whom 24 h ABPM was performed at 28-32 weeks of pregnancy. The obstetric and perinatal outcomes were evaluated. Results: Two hundred patients were included. Thirty-seven women with GDM and obesity had significantly higher mean systolic BP (SBP) and nocturnal SBP and diastolic BP (DBP) compared to women with only GDM (n = 86). Nocturnal SBP (OR = 1.077; p = 0.015) and obesity (OR = 1.131; p = 0.035) were risk factors for the development of hypertensive disorders of pregnancy (HDPs). Mothers of newborns with neonatal complications (n = 27) had higher nocturnal SBP (103.8 vs. 100 mmHg; p = 0.047) and DBP (62.7 vs. 59.4; p = 0.016). Women who delivered preterm (n = 10) had higher BP and a non-dipper pattern (p = 0.005). Conclusions: Nocturnal SBP was a predictor of HDPs in normotensive women with obesity or GDM. Alterations in ABPM in these patients were associated with poor obstetric and perinatal outcomes.},
organization = {This research was funded by the Instituto de Salud Carlos III, grant number "PI16/00370" (co-funded by the European Regional Development Fund, ERDF), and the Biomedical Research and Innovation Institute of Cadiz (INiBICA).},
publisher = {MDPI},
keywords = {gestational diabetes mellitus},
keywords = {ambulatory blood pressure monitoring},
keywords = {hypertensive disorders of pregnancy},
keywords = {perinatal outcomes},
title = {Blood Pressure Monitoring and Perinatal Outcomes in Normotensive Women with Gestational Diabetes Mellitus},
doi = {10.3390/jcm11051435},
author = {Lara-Barea, Almudena and Sánchez-Lechuga, Begoña and Vidal-Suárez, Álvaro and Arroba Espinosa, Ana Isabel and Bugatto González, Fernando and López Tinoco, Cristina},
}