@misc{10498/26712, year = {2022}, month = {3}, url = {http://hdl.handle.net/10498/26712}, abstract = {The compounds 11,12,13-tri-nor-sesquiterpenes are degraded sesquiterpenoids which have lost the C-3 unit of isopropyl or isopropenyl at C-7 of the sesquiterpene skeleton. The irregular C-backbone originates from the oxidative removal of a C-3 side chain from the C-15 sesquiterpene, which arises from farnesyl diphosphate (FDP). The C-12 -framework is generated, generally, in all families of sesquiterpenes by oxidative cleavage of the C-3 substituent, with the simultaneous introduction of a double bond. This article reviews the isolation, biosynthesis and biological activity of this special class of sesquiterpenes, the 11,12,13-tri-nor-sesquiterpenes.}, organization = {This research was supported by grant from MICIU (RTI2018-097356-B-C21, MCIU/AEI/FEDER, EU).}, publisher = {MDPI}, keywords = {11,12,13-tri-nor-sesquiterpenes}, keywords = {isolation}, keywords = {biosynthesis}, keywords = {biological activity}, title = {Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites}, doi = {10.3390/plants11060769}, author = {Coca Ruiz, Víctor and Suárez Cáceres, Ivonne Rocío and Aleu Casatejada, Josefina and González Collado, Isidro}, }