@misc{10498/28691,
year = {2022},
month = {10},
url = {http://hdl.handle.net/10498/28691},
abstract = {The detection of analytes in complex organic matrices requires a series of analytical steps to obtain a reliable analysis. Sample preparation can be the most time-consuming, prolonged, and error-prone step, reducing the reliability of the investigation. This review aims to discuss the advantages and limitations of extracting bioactive compounds, sample preparation techniques, automation, and coupling with on-line detection. This review also evaluates all publications on this topic through a longitudinal bibliometric analysis, applying statistical and mathematical methods to analyze the trends, perspectives, and hot topics of this research area. Furthermore, state-of-the-art green extraction techniques for complex samples from vegetable matrices coupled with analysis systems are presented. Among the extraction techniques for liquid samples, solid-phase extraction was the most common for combined systems in the scientific literature. In contrast, for on-line extraction systems applied for solid samples, supercritical fluid extraction, ultrasound-assisted extraction, microwave-assisted extraction, and pressurized liquid extraction were the most frequent green extraction techniques.},
publisher = {MDPI},
keywords = {sample preparation},
keywords = {green extraction techniques},
keywords = {on-line coupling},
keywords = {fully automated analysis},
keywords = {bibliometric analysis},
title = {Green Extraction Processes for Complex Samples from Vegetable Matrices Coupled with On-Line Detection System: A Critical Review},
doi = {10.3390/molecules27196272},
author = {Maciel-Silva, Francisco W. and Lachos-Perez, Daniel and Selene Buller, Luz and Sganzerla, William G. and Pérez García, Montserrat and Rostagno, Mauricio Ariel and Forster-Carneiro, Tânia},
}