@misc{10498/30688,
year = {2015},
month = {5},
url = {http://hdl.handle.net/10498/30688},
abstract = {Background: Transcranial static magnetic field stimulation (tSMS) in humans reduces cortical excitability.

Objective: The objective of this study was to determine if prolonged tSMS (2 h) could be delivered safely in humans. Safety limits for this technique have not been described.

Methods: tSMS was applied for 2 h with a cylindric magnet on the occiput of 17 healthy subjects. We assessed tSMS-related safety aspects at tissue level by measuring levels of neuron-specific enolase (NSE, a marker of neuronal damage) and S100 (a marker of glial reactivity and damage). We also included an evaluation of cognitive side effects by using a battery of visuomotor and cognitive tests.

Results: tSMS did not induce any significant increase in NSE or S100. No cognitive alteration was detected.

Conclusions: Our data indicate that the application of tSMS is safe in healthy human subjects, at least within these parameters.},
publisher = {ELSEVIER SCIENCE BV},
keywords = {NIBS},
keywords = {Neuron-specific enolase},
keywords = {Repetitive transcranial magnetic stimulation (rTMS)},
keywords = {S100},
keywords = {Safety},
keywords = {Transcranial static magnetic field stimulation (tSMS)},
title = {Safety Study of Transcranial Static Magnetic Field Stimulation (tSMS) of the Human Cortex},
doi = {10.1016/j.brs.2014.12.002},
author = {Oliviero, A and Carrasco-López, MC and Campolo, M and Perez-Borrego, Y and Soto Leon, Vanesa and González Rosa, Javier Jesús and Higuero, AM and Strange, BA and Abad-Rodriguez, J and Foffani, G},
}