@misc{10498/31201, year = {2023}, month = {2}, url = {http://hdl.handle.net/10498/31201}, abstract = {Dietary additives have the potential to stimulate the whiteleg shrimp immune system, but information is scarce on their use in diets for larval/post-larval stages. The potential beneficial effects of vitamins C and E, β-glucans, taurine, and methionine were evaluated. Four experimental microdiets were tested: a positive control diet (PC); the PC with decreased levels of vitamin C and E as negative control (NC); the PC with increased taurine and methionine levels (T + M); and the PC supplemented with β-glucans (BG). No changes in growth performance and survival were observed. However, post-larvae shrimp fed the NC had lower relative expressions of pen-3 than those fed the PC, suggesting that lower levels of vitamins C and E may impact the shrimp immune status. Lipid peroxidation levels dropped significantly in the BG compared to the PC, indicating that β-glucans improved the post-larvae antioxidant mechanisms. Furthermore, when compared with the NC diet, PL fed with BG showed significant increases in tGSH levels and in the relative expression of crus and pen-3, suggesting a synergistic effect between vitamins C and E and β-glucans. Amongst the additives tested, β-glucans seems to be the most promising even when compared to a high-quality control diet}, publisher = {MDPI}, keywords = {antioxidants}, keywords = {dietary additives}, keywords = {health status}, keywords = {immunostimulants}, keywords = {microdiets}, keywords = {Penaeus vannamei}, keywords = {post larvae}, keywords = {whiteleg shrimp}, title = {Health-Promoting Additives Supplemented in Inert Microdiets for Whiteleg Shrimp (Penaeus vannamei) Post-Larvae: Effects on Growth, Survival, and Health Status}, doi = {10.3390/ani13040726}, author = {Barreto, André and Peixoto, Diogo and Fajardo Quiñones, Carlos and Pinto, Wilson and Rocha, Rui J. M. and Conceição, Luís E. C. and Costas, Benjamín}, }