@misc{10498/31476, year = {2023}, url = {http://hdl.handle.net/10498/31476}, abstract = {Scolymus hispanicus L., also known as golden thistle, Spanish oyster thistle or, more commonly, as tagarnina is a plant that belongs to the Asteraceae family. It is collected from the wild for human consumption in Mediterranean countries. It is a relevant ingredient in Andalusian culinary culture, where the midribs of young plants are harvested for consumption. Scolymus hispanicus L. contains a wide variety of phenolic compounds such as caffeoylquinic acids (CQAs), among others. In the present work, the major phenolic compounds present in tagarnina have been identified, with 5-caffeoylquinic acid (5-CQA) and 3,5-dicaffeoylquinic acid (3,5-diCQA) being the main ones. A method based on ultrasound-assisted extraction (UAE) has been developed for the extraction of these compounds, with the percentage of methanol, sample-to-solvent ratio and the pH being the most influential factors. The developed method has been validated and employed to determine the concentration of 5-CQA and 3,5-diCQA in the midribs of Scolymus hispanicus, collected in six different places in the south of Spain. The antioxidant activity of the samples has also been determined, and a direct correlation with their caffeoylquinic compounds content has been established, showing an antioxidant effect.}, publisher = {MDPI}, keywords = {Scolymus hispanicus}, keywords = {caffeoylquinic acids}, keywords = {ultrasound-assisted extraction;}, keywords = {antioxidant properties}, keywords = {phenolic compounds}, keywords = {golden thistle}, title = {Determination of Caffeoylquinic Acids Content by UHPLC in Scolymus hispanicus Extracts Obtained through Ultrasound-Assisted Extraction}, doi = {10.3390/PLANTS12122340}, author = {Ruano González, Antonio and Pinto, Ana Andreina and Chinchilla Salcedo, Nuria and Palma Lovillo, Miguel and Fernández Barbero, Gerardo and Carrera Fernández, Ceferino Adrián and Vázquez Espinosa, Mercedes}, }