@misc{10498/31755,
year = {2023},
url = {http://hdl.handle.net/10498/31755},
abstract = {This study focuses on developing hydroxyapatite synthesized from a CaCO3
-rich byproduct of sugar beet processing called Carbocal® using a hydrothermal reactor. The purpose of this
biomaterial is to enhance the osteoinductivity of implantable surfaces and serve as a bone filler,
providing a sustainable and economically more affordable alternative. This research involved compositional analysis and micro- and macrostructural physicochemical characterization, complemented
with bioactivity and live/dead assays. The biphasic nature of the Carbocal®-derived sample was
significant within the context of the bioactivity concept previously proposed in the literature. The
bioactivity of the biomaterial was demonstrated through a viability test, where the cell growth was
nearly equivalent to that of the positive control. For comparison purposes, the same tests were
conducted with two additional samples: hydroxyapatite obtained from CaCO3 and commercial
hydroxyapatite. The resulting product of this process is biocompatible and possesses properties
similar to natural hydroxyapatite. Consequently, this biomaterial shows potential as a scaffold in
tissue engineering and as an adhesive filler to promote bone regeneration within the context of the
circular bioeconomy in the geographical area proposed.},
organization = {Junta de Andalucía},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
keywords = {Biphasic bioceramic},
keywords = {Hydroxyapatite},
keywords = {Carbocal®},
keywords = {Viability},
keywords = {Bioactive coating},
keywords = {Bone cement},
title = {Biphasic Bioceramic Obtained from Byproducts of Sugar Beet Processing for Use in Bioactive Coatings and Bone Fillings},
doi = {10.3390/jfb14100499},
author = {Suffo Pino, Miguel and Cauqui López, Miguel Ángel and Pérez Muñoz, Celia and Goma Jiménez, Daniel and Fernández Delgado, Natalia and Herrera Collado, Miriam},
}