@misc{10498/32030,
year = {2023},
url = {http://hdl.handle.net/10498/32030},
abstract = {Background: One of the side effects of anti-estrogen treatments in breast cancer survivors (BCSs), especially with aromatase inhibitor (AI) treatment, is the frequent appearance of vulvo-vaginal atrophy (VVA). We aim to evaluate the efficacy, safety and feasibility of a new type of non-ablative Solid-State Vaginal Laser (SSVL) treatment in BCSs with VVA. Methods: A total of 30 BCSs with a history of AI use and symptoms of VVA were treated with a non-ablative SSVL (LASEmaR 1500™-EUFOTON)in this non-randomized pilot study. The effects of the laser have been evaluated at baseline, 10 wk and 24 wk using a visual analogue scale (VAS), the Vaginal Health Index (VHI), the Vulvar Health Index (VuHI), the Female Sexual Function Index (FSFI), the EORTC QLQ-BR23, the Vaginal Maturation Index (VMI) and vaginal pH. Results: At 10-week follow-up vs. baseline there were no statistically significant differences in FSFI, lubrication and EORTC QLQ-BR23. In all the subjective (dyspareunia, VHI, VuHI, FSFI, QLQ) and objective parameters (VMI and pH) there was a statistically significant improvement at the 6-month follow-up. Satisfaction was very high (4.7 out of 5), with 95.7% of patients being satisfied, more than or very satisfied. Conclusions: Preliminary results of SSVL treatment of VVA and dyspareunia in BCSs after AI treatment suggest clinical improvement, without relevant side effects and with a high degree of satisfaction.},
publisher = {Multidisciplinary Digital Publishing Institute (MDPI)},
keywords = {aromatase inhibitors},
keywords = {breast cancer survivors},
keywords = {non-ablativesolid-state vaginal laser (SSVL)},
keywords = {vulvo-vaginal atrophy (VVA)},
title = {Effects of Non-Ablative Solid-State Vaginal Laser (SSVL) for the Treatment of Vulvovaginal Atrophy in Breast Cancer Survivors after Adjuvant Aromatase Inhibitor Therapy: Preliminary Results},
doi = {10.3390/JCM12175669},
author = {Lubián López, Daniel María and Butrón-Hinojo, Carmen Aisha and Menjón-Beltrán, S. and González-Mesa, Ernesto and Tapiador-Albertos, S. and Rodríguez-Jiménez, B. and Fiol-Ruiz, G.},
}