@misc{10498/33106,
year = {2021},
url = {http://hdl.handle.net/10498/33106},
abstract = {Background: Cocaine use is a growing global health problem and patients with cocaine use disorders (CUD) present several complications, including high rates of major depression. These subjects present two types of major depressive disorder (MDD): primary major depressive disorder (P-MDD) and cocaine-induced major depressive disorder (CI-MDD). To improve treatment, it is necessary to distinguish between both types. The aim of this study was to assess the differences in depressive symptomatology criteria (P-MDD vs CI-MDD) in CUD patients.

Methods: Secondary data analysis was carried out with a cross-sectional sample of 160 patients presenting CUD and MDD. Clinical assessment was performed using the Psychiatric Research Interview for Substance and Mental Disorders (PRISM). A differential diagnosis was obtained between P-MDD and CI-MDD.

Results: Men represented 80% of the sample, the mean age was 38.61 years, and 64.5% had elementary studies. CI-MDD diagnosis (61.3%) was more frequent than P-MDD (38.7%). There was a younger age of CUD onset in CI-MDD patients. In addition, 79.4% of the patients had another substance use disorder diagnosis. The criterion "Changes in weight or appetite" was more prevalent (57.1%) in P-MDD group.

Conclusions: We found differences in the criterion "Changes in weight or appetite". Further research is needed in this field to establish a differential diagnosis and thus provide better treatment for CUD patients.},
keywords = {Dual diagnosis},
keywords = {cocaine use disorder},
keywords = {cocaine-related disorders},
keywords = {depressive disorder},
keywords = {induced depression},
title = {Cocaine and depressive disorders: When standard clinical diagnosis is insufficient},
doi = {10.20882/adicciones.1321},
author = {Alías-Ferri, María and García-Marchena, Nuria and Mestre-Pintó, Joan and Araos, Pedro and Vergara Moragues, Esperanza and Fonseca, Francina and González Saiz, Francisco Manuel and Rodríguez de Fonseca, Fernando and Torrens, Marta and NEURODEP, Group},
}