@misc{10498/34727, year = {2013}, month = {3}, url = {http://hdl.handle.net/10498/34727}, abstract = {A chemical study of the alga Cystoseira usneoides has led to the isolation of six new meroterpenoids, cystodiones A−F (1−6), together with six known related compounds (7−12). The structures of the new metabolites have been established by spectroscopic techniques. In antioxidant assays all of the tested meroterpenes, and in particular cystodiones A (1) and B (2), 6-cis-amentadione-1′-methyl ether (7), and amentadione-1′ methyl ether (8), exhibited strong radical-scavenging activity. In antiinflammatory assays, usneoidone Z (11) and its corresponding 6E isomer (12) showed significant activity as inhibitors of the production of the proinflammatory cytokine TNF-α in LPS-stimulated THP-1 human macrophages.}, publisher = {ACS}, title = {Antioxidant and Anti-inflammatory Meroterpenoids from the Brown Alga Cystoseira usneoides}, doi = {10.1021/np300833y}, author = {Reyes Jiménez, Carolina de los and Zbakh, Hanna and Motilva, Virginia and Zubía Mendoza, Eva}, }