@misc{10498/38602,
year = {2026},
url = {http://hdl.handle.net/10498/38602},
abstract = {Cortico-subcortical dysfunction from dopaminergic depletion is a hallmark of Parkinson's disease (PD). Modulating primary motor cortex (M1) excitability with intermittent theta burst stimulation (iTBS) may restore network integrity in PD by targeting neurobiological changes at excitatory, structural, and serological levels. This study aimed to demonstrate the clinical and neurobiological effects of bilateral M1 iTBS in patients with PD.
Bilateral M1 iTBS may represent a valuable adjunctive therapeutic option for pharmacological treatment of motor symptoms in patients with PD by promoting structural brain changes and enhancing synaptic plasticity in intermediate disease stages.},
publisher = {Springer Nature},
keywords = {Intermittent theta burst stimulation},
keywords = {Neurodegeneration and neuroplasticity serum biomarkers},
keywords = {Parkinson’s disease},
keywords = {Structural brain imaging},
title = {Plasticity-Induced Motor Recovery of Bilateral Intermittent Theta Burst Stimulation in Parkinson's Disease: A Randomized, Double-Blind, Sham-Controlled, Crossover Trial},
doi = {10.1007/s40120-025-00865-0},
author = {Rashid Abdu Rahim López, Raúl and Macías García, Paloma and Cruz Gómez, Álvaro Javier and Cano Cano, Fátima and Sánchez Fernández, Francisco Luis and Sarrias Arrabal, Esteban and Marco Delgado, Ángel José del and González Moraleda, Álvaro Antonio and Lozano Soto, Elena María and Sanmartino, Florencia Soledad and Espinosa Rosso, Raúl and González Rosa, Javier Jesús},
}