%0 Journal Article 
%A Dubey, Rashmi
%A Kumar Tewari, Ashish
%A Prakash Singh, Ved
%A Singh, Praveen
%A Singh Dangi, Jawahar
%A Puerta, M. Carmen
%A Valerga, Pedro
%A Kant, Rajni
%T Molecular Docking Study of Conformational Polymorph: Building Block of Crystal Chemistry
%D 2013
%U http://hdl.handle.net/10498/20430
%X Two conformational polymorphs of novel 2-[2-(3-cyano-4,6-dimethyl-2-oxo-2H-pyridin-1-yl)-ethoxy]-4,6-dimethyl nicotinonitrile have been developed. The crystal structure of both polymorphs (1a and 1b) seems to be stabilized by weak interactions. A difference was observed in the packing of both polymorphs. Polymorph 1b has a better binding affinity with the cyclooxygenase (COX-2) receptor than the standard (Nimesulide).
%~ Universidad de Cádiz