%0 Journal Article 
%A Coca Ruiz, Víctor
%A Suárez Cáceres, Ivonne Rocío
%A Aleu Casatejada, Josefina
%A González Collado, Isidro
%T Structures, Occurrences and Biosynthesis of 11,12,13-Tri-nor-Sesquiterpenes, an Intriguing Class of Bioactive Metabolites
%D 2022
%@ 2223-7747
%U http://hdl.handle.net/10498/26712
%X The compounds 11,12,13-tri-nor-sesquiterpenes are degraded sesquiterpenoids which have lost the C-3 unit of isopropyl or isopropenyl at C-7 of the sesquiterpene skeleton. The irregular C-backbone originates from the oxidative removal of a C-3 side chain from the C-15 sesquiterpene, which arises from farnesyl diphosphate (FDP). The C-12 -framework is generated, generally, in all families of sesquiterpenes by oxidative cleavage of the C-3 substituent, with the simultaneous introduction of a double bond. This article reviews the isolation, biosynthesis and biological activity of this special class of sesquiterpenes, the 11,12,13-tri-nor-sesquiterpenes.
%K 11,12,13-tri-nor-sesquiterpenes
%K isolation
%K biosynthesis
%K biological activity
%~ Universidad de Cádiz