%0 Journal Article 
%A Moraga, Javier
%A Suárez Cáceres, Ivonne Rocío
%A Silva Lima, Gesiane de
%A Conti, Raphael
%A Pinedo Rivilla, Cristina
%A Moraga Galindo, Javier
%A Barúa, Javier E.
%A Oliveira, Ana Ligia de
%A Aleu Casatejada, Josefina
%A Durán Patrón, Rosa María
%A Macías Sánchez, Antonio José
%A Hanson, J. R.
%A Tallarico Pupo, Monica
%A Hernández Galán, Rosario
%A González Collado, Isidro
%T Structural and biosynthetic studies on eremophilenols related to the phytoalexin capsidiol, produced by Botrytis cinerea
%D 2018
%@ 0031-9422
%U http://hdl.handle.net/10498/30244
%X A thorough study of the fermentation broth of three strains of Botrytis cinerea which were grown on a modified
Czapek-Dox medium supplemented with 5 ppm copper sulphate, yielded five undescribed metabolites. These
metabolites possessed a sesquiterpenoid (+)-4-epi-eremophil-9-ene carbon skeleton which was enantiomeric to
that of the phytoalexin, capsidiol. The isolation of these metabolites when the fungus was stressed, suggests that
they may be potential effectors used by B. cinerea to circumvent plant chemical defences against phytopatho genic fungi. The biosynthesis of these compounds has been studied using 2
H and 13C labelled acetate
%K Botrytis cinerea
%K Sclerotiniaceae
%K Biosynthesis
%K Cryptic metabolites
%K Eremophilenols
%~ Universidad de Cádiz