%0 Journal Article 
%A Ruano González, Antonio
%A Pinto, Ana Andreina
%A Chinchilla Salcedo, Nuria
%A Palma Lovillo, Miguel
%A Fernández Barbero, Gerardo
%A Carrera Fernández, Ceferino Adrián
%A Vázquez Espinosa, Mercedes
%T Determination of Caffeoylquinic Acids Content by UHPLC in Scolymus hispanicus Extracts Obtained through Ultrasound-Assisted Extraction
%D 2023
%@ 2223-7747
%U http://hdl.handle.net/10498/31476
%X Scolymus hispanicus L., also known as golden thistle, Spanish oyster thistle or, more commonly, as tagarnina is a plant that belongs to the Asteraceae family. It is collected from the wild for
human consumption in Mediterranean countries. It is a relevant ingredient in Andalusian culinary
culture, where the midribs of young plants are harvested for consumption. Scolymus hispanicus L.
contains a wide variety of phenolic compounds such as caffeoylquinic acids (CQAs), among others.
In the present work, the major phenolic compounds present in tagarnina have been identified, with
5-caffeoylquinic acid (5-CQA) and 3,5-dicaffeoylquinic acid (3,5-diCQA) being the main ones. A
method based on ultrasound-assisted extraction (UAE) has been developed for the extraction of
these compounds, with the percentage of methanol, sample-to-solvent ratio and the pH being the
most influential factors. The developed method has been validated and employed to determine the
concentration of 5-CQA and 3,5-diCQA in the midribs of Scolymus hispanicus, collected in six different
places in the south of Spain. The antioxidant activity of the samples has also been determined, and
a direct correlation with their caffeoylquinic compounds content has been established, showing an
antioxidant effect.
%K Scolymus hispanicus
%K caffeoylquinic acids
%K ultrasound-assisted extraction;
%K antioxidant properties
%K phenolic compounds
%K golden thistle
%~ Universidad de Cádiz