%0 Journal Article 
%A Suffo Pino, Miguel
%A Cauqui López, Miguel Ángel
%A Pérez Muñoz, Celia
%A Goma Jiménez, Daniel
%A Fernández Delgado, Natalia
%A Herrera Collado, Miriam
%T Biphasic Bioceramic Obtained from Byproducts of Sugar Beet Processing for Use in Bioactive Coatings and Bone Fillings
%D 2023
%@ 2079-4983
%U http://hdl.handle.net/10498/31755
%X This study focuses on developing hydroxyapatite synthesized from a CaCO3
-rich byproduct of sugar beet processing called Carbocal® using a hydrothermal reactor. The purpose of this
biomaterial is to enhance the osteoinductivity of implantable surfaces and serve as a bone filler,
providing a sustainable and economically more affordable alternative. This research involved compositional analysis and micro- and macrostructural physicochemical characterization, complemented
with bioactivity and live/dead assays. The biphasic nature of the Carbocal®-derived sample was
significant within the context of the bioactivity concept previously proposed in the literature. The
bioactivity of the biomaterial was demonstrated through a viability test, where the cell growth was
nearly equivalent to that of the positive control. For comparison purposes, the same tests were
conducted with two additional samples: hydroxyapatite obtained from CaCO3 and commercial
hydroxyapatite. The resulting product of this process is biocompatible and possesses properties
similar to natural hydroxyapatite. Consequently, this biomaterial shows potential as a scaffold in
tissue engineering and as an adhesive filler to promote bone regeneration within the context of the
circular bioeconomy in the geographical area proposed.
%K Biphasic bioceramic
%K Hydroxyapatite
%K Carbocal®
%K Viability
%K Bioactive coating
%K Bone cement
%~ Universidad de Cádiz