%0 Journal Article 
%A Beltrán, A.M.
%A Manuel Delgado, José Manuel
%A Litrán Ramos, Rocío
%A Félix Ruiz, Eduardo José
%A Santos Izquierdo-Bueno, Antonio Jesús
%A Morales Sánchez, Francisco Miguel
%A Bomati Miguel, Óscar
%T (S)TEM structural and compositional nanoanalyses of chemically synthesized glutathione-shelled nanoparticles
%D 2020
%@ 2190-5517

%U http://hdl.handle.net/10498/34328
%X This work is focused on the characterization by Transmission and Scanning Transmission Electron Microscopy related techniques of core-shell nanoparticles
synthesized via chemical methods. Different semiconducting, pure metallic or oxide
materials have been utilized as the core (CdTe, Au, Fe 3 O 4 , or Fe 3 O 4
covered with Au) of the nanoparticle, while they have been, in all cases, functionalized
by a thin amorphous glutathione layer, with the goal of using the NPs in biomedical
applications such as biomarkers, and computerized tomography and image magnetic
resonance contrast agents. The results show that it is possible to visualize the
glutathione layer using spectroscopic and imaging techniques, associated to electron
microscopy (such as energy dispersive X-ray spectroscopy and high-resolution
transmission electron microscopy images), that this layer is present at the surfaces of
all observed nanoparticles, and that it is no thicker than a few nanometers. Electron
microscopy also revealed that the nanoparticles core are crystalline and, in average,
around 5-nm-size
%~ Universidad de Cádiz