%0 Journal Article 
%A Gallardo Herrerías, Celia
%T Persistent COVID and ASD: Long-term neuropsychiatric impact and the need for personalized interventions

%D 2025
%@ 2341-3255
%U http://hdl.handle.net/10498/36743
%X The study explores the long-term neuropsychiatric impact of COVID-19 on individuals with
Autism Spectrum Disorders (ASD) in order to develop effective interventions and treatments.
The primary objective was to examine the impact of COVID-19 on long-term
neuropsychiatric symptoms in ASD patients and determine the optimal treatment and
management options. A systematic review was performed using scientific databases such as
PubMed, Scopus, Web of Science, and Redalyc, with major key words and strict
inclusion/exclusion criteria to ensure the quality of the study. Of the 242 studies initially
reported, 12 met all the inclusion criteria for the review. The outcomes showed that repeat
COVID aggravates pre-existing neuropsychiatric signs in ASD individuals, mainly
depression and anxiety. Meta-analysis of the combined studies showed an increase of 1.5
points on a common symptom score after COVID-19. Irritability and emotion regulation
were also identified as other behavioral problems. Overall, COVID-19 impacts the
neuropsychiatric health of ASD individuals adversely and demands tailored and
multidisciplinary treatment methods targeting physical as well as psychiatric symptoms.

%K Long COVID
%K ASD
%K Autism
%K mental health
%K COVID persistente
%K TEA
%K salud mental
%~ Universidad de Cádiz