%0 Journal Article 
%A Escudier-Vázquez, Juan Manuel
%A Ruiz-Muñoz, Manuel
%A Garrido-Palomino, Inmaculada
%A Ortega Gómez, Sonia
%A Valmisa Gómez de Lara, Eulalio Juan
%A Espinosa Nogales, María del Mar
%A Viglerio Montero, Alicia
%A Rosety Rodríguez, Miguel Ángel
%A Jiménez Pavón, David
%A Carbonell Baeza, Ana
%A España Romero, Vanesa
%T Internet-Based Psycho-Physical Exercise Intervention Program in Mild-to-Moderate Depression: The Study Protocol of the SONRIE Randomized Controlled Trial
%D 2025
%@ 1660-4601

%U http://hdl.handle.net/10498/38096
%X The COVID-19 pandemic has intensified depression due to isolation and reduced physical activity, highlighting the need for accessible remote treatments. The SONRIE study evaluates the effectiveness of a 12-week online intervention combining physical exercise and internet-based cognitive–behavioral therapy on depressive symptoms in adults with mild-to-moderate depression. This randomized controlled trial involved 80 adults aged 25–65 years diagnosed with depression according to the ICD-10 criteria. Participants were randomized to an experimental group receiving the combined online intervention or to a control group receiving standard care. The primary outcome was the change in depression severity, assessed by the Beck Depression Inventory, with outcomes measured at baseline, immediately post-intervention, and after an 8-week follow-up phase. Statistical analyses include analysis of covariance to compare group changes over time, with effect sizes quantifying the intervention’s impact. The SONRIE study demonstrates a promising online approach for treating depression, with potential implications for clinical practice and public health strategies.
%K depression
%K endocannabinoid system
%K internet-based cognitive–behavioral therapy
%K mental health
%K physical exercise
%K randomized controlled trial
%~ Universidad de Cádiz