http://hdl.handle.net/10498/17425 Thu, 05 Nov 2026 16:22:19 GMT 2026-11-05T16:22:19Z http://hdl.handle.net/10498/32089 Notas de anatomía humana Casar Artes, Juan; Casar García, Juan; Carrasco Molinillo, María del Carmen; Pérez Arana, Gonzalo Martín; Ribelles García, Antonio; Prada Oliveira, José Arturo Notas del profesorado editadas y corregidas para facilitar el aprendizaje de las asignaturas de Anatomía humana que impartimos, especialmente diseñado en la profundidad de los contenidos para los grados universitarios de Enfermería, Fisioterapia y Ciencias de la Actividad Física y del Deporte. Wed, 01 Apr 2020 00:00:00 GMT http://hdl.handle.net/10498/32089 2020-04-01T00:00:00Z http://hdl.handle.net/10498/32087 MANUAL DE SIMULACIÓN DE TÉCNICAS INVASIVAS EN CADÁVERES Gracia-Romero, Manuel Angel; Estella-García, Angel; Díaz Gómez, Alfredo Luis; Fernández-Ruiz, A.; Pérez-Arana, Gonzalo; Prada-Oliveira, Jose-Arturo; Ribelles-Garcia, Antonio; Romero-Bermejo, Francisco-José Este libro ha sido concebido desde la certeza que tenemos todos los autores de que la mejor alternativa es siempre la colaboración. Se trata de un libro donde colaboran profesionales del ámbito médico de distintas especialidades y ramas del conocimiento. Pero también es una colaboración donde se aproximan dos perspectivas del aprendizaje de la medicina: el conocimiento de las ciencias médicas básicas, como es la anatomía humana, y el adiestramiento y la práctica clínica directa con técnicas avanzadas empleadas sobre el paciente en el manejo clínico hospitalario. En resumen, en estas páginas queremos plasmar cómo el abordaje de las necesidades e inquietudes clínicas pueden ser abordadas desde el conocimiento de los bases de la medicina, como es la anatomía. Queremos que nuestros lectores tengan un manual sencillo y resolutivo que le acompañe en el aprendizaje de técnicas complejas. Esta obra plasma el material docente complementario de los cursos que los autores del libro desarrollan en cursos de alta especialización, orientado al manejo de situaciones vitales altamente complejas. Libro empleado y diseñado como material de apoyo específico para el aprendizaje de técnicas clínicas especializadas. Wed, 01 Nov 2023 00:00:00 GMT http://hdl.handle.net/10498/32087 2023-11-01T00:00:00Z http://hdl.handle.net/10498/27842 Peptide Tyrosine-Tyrosine Triggers GLP-2-Mediated Intestinal Hypertrophy After Roux-en-Y Gastric Bypass Pérez Arana, Gonzalo Martín; Díaz Gómez, Alfredo Luis; Camacho Ramírez, Alonso; Ribelles García, Antonio; Almorza Gomar, David; Gracia Romero, Manuel Ángel; Prada Oliveira, José Arturo Purpose Intestinal remodeling and adaptation of the alimentary limb after Roux-en-Y gastric bypass (RYGB) play an important role in the pathophysiological events that lead to type 2 diabetes mellitus (T2DM) improvement. Intestinal absorptive loop hypertrophy and growth following surgery have been related to GLP-2 secretion by ileal L-cells. The secretion of peptide tyrosine-tyrosine (PYY) enterohormone after a meal has been proposed as a trigger for ileal secretion of GLP-1. Our aim is to determine the role of PYY as a GLP-2 secretion modulator as an adaptation result in the alimentary limb after RYGB. Method We used a non-obese euglycemic rodent model. Circulating glucose, insulin, PYY, and GLP-2 were measured in the experimental and control groups. We used four groups: fasting control, Sham-operated, RYGB-operated (RYGB), and RYGB-operated and treated with BIIE0246 (RYGB + BII). BIIE0246 is a NPY2 receptor antagonist in L-cells. Intestinal glucose transporters and GLP-1 and PYY gut expression and hypertrophy were analyzed after 12 weeks of surgery. Results RYGB increased PYY3-36 plasma levels in rats with or without BIT treatment. A high-insulin response was observed in the RYGB group but not in the control or RYGB +BII groups. BIIE0246 treatment limited plasma GLP-2 levels. In the alimentary intestinal limb, hypertrophy and SGLT1 and GLUT1 expression appeared to be reduced after RYGB compared to controls. Conclusion The postprandial ileal PYY secretion is enhanced after RYGB. This increase mediates GLP-2 release through its binding to the Y2 receptor on L-cells. This mechanism plays a role in alimentary limb hypertrophy after surgery. Thu, 01 Dec 2022 00:00:00 GMT http://hdl.handle.net/10498/27842 2022-12-01T00:00:00Z http://hdl.handle.net/10498/27288 Peptide tyrosine-tyrosine triggers GLP-2-mediated intestinal hypertrophy after Roux en-Y gastric bypass. Pérez Arana, Gonzalo Martín; Prada Oliveira, José Arturo Intestinal remodeling and adaptation of the alimentary limb after Roux en-Y gastric bypass (RYGB) play an important role in the pathophysiological events that lead to type 2 diabetes mellitus (T2DM) improvement. Intestinal absorptive loop hypertrophy and growth following surgery have been related to GLP-2 secretion by ileal L-cells. The secretion of PYY enterohormone after a meal has been proposed as a trigger for ileal secretion of GLP-1. Our aim is to determine the role of PYY as a GLP-2 secretion modulator as an adaptation result in the alimentary limb after RYGB. To this, we used a nonobese euglycemic rodent model. Circulating glucose, insulin, PYY and GLP-2 were measured in the experimental and control groups. We used four groups: Fasting Control, Sham-operated, RYGB-operated (RYGB) and RYGB-operated and treated with BIIE0246 (RYGB+BII). BIIE0246 is a NPY2 receptor antagonist in L-cells. Intestinal glucose transporters and GLP-1 and PYY gut expression and hypertrophy were analyzed after twelve weeks of surgery. RYGB increased PYY3-36 plasma levels in rats with or without BII treatment. A high insulin response was observed in the RYGB group but not in the control or RYGB+BII groups. BIIE0246 treatment limited plasma GLP-2 levels. In the alimentary intestinal limb, hypertrophy and SGLT1 and GLUT1 expression appeared to be reduced after RYGB compared to the other groups. We concluded that postprandial ileal PYY secretion is enhanced after RYGB. This increase mediates GLP-2 release through its binding to the Y2 receptor on L-cells. This mechanism plays a role in alimentary limb hypertrophy after surgery. Sat, 20 Aug 2022 00:00:00 GMT http://hdl.handle.net/10498/27288 2022-08-20T00:00:00Z