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dc.contributor.authorMarín-Barrios, Rubén
dc.contributor.authorGarcía-Cabeza, Ana Leticia
dc.contributor.authorMoreno-Dorado, F. Javier
dc.contributor.authorGuerra, Francisco M.
dc.contributor.authorMartínez Massanet, Guillermo
dc.contributor.otherQuímica Orgánicaen_US
dc.date.accessioned2018-04-19T12:15:55Z
dc.date.available2018-04-19T12:15:55Z
dc.date.issued2014-06
dc.identifier.urihttp://hdl.handle.net/10498/20367
dc.description.abstractThe α′-acyloxylation of cyclic enones with linear carboxylic acids is described. The reaction is promoted by KMnO4 in the presence of a carboxylic acid and its corresponding carboxylic anhydride. The optimization of the reaction has been carried out using the statistical methodology known as design of experiments. The optimized reaction conditions have been evaluated in terms of substrate scope and compatibility with different functional groups. The methodology has been applied to the synthesis of densely oxygenated guaianes and guaianolides.en_US
dc.formatapplication/pdfen_US
dc.language.isoengen_US
dc.publisherACS Publicationsen_US
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.sourceJournal of Organic Chemistry 2014, 79, 6501−6509en_US
dc.titleAcyloxylation of Cyclic Enones: Synthesis of Densely Oxygenated Guaianolidesen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.identifier.doi10.1021/jo500915r


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Attribution-NonCommercial-NoDerivatives 4.0 Internacional
This work is under a Creative Commons License Attribution-NonCommercial-NoDerivatives 4.0 Internacional