Gonadotrophin inhibitory hormone down-regulates the brain-pituitary reproductive axis of male European sea bass (Dicentrarchus labrax)

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URI: http://hdl.handle.net/10498/34508

DOI: https://doi.org/10.1095/biolreprod.116.139022

ISSN: 0006-3363

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Author/s
Paullada Salmerón, José AntonioAuthority UCA; Cowan, Mairi E.; Aliaga Guerrero, María; Zanuy, Silvia; Muñoz Cueto, José AntonioAuthority UCA
Date
2016
Department
Biología; Biomedicina, Biotecnología y Salud Pública
Source
Biology of Reproduction, Vol. 94, Núm. 6, 2016
Abstract
This study was the first to implement intracerebroventricular (icv) injections to assess the effects of GnIH in fish, marking a methodological shift from earlier in vitro and intraperitoneal approaches. The results demonstrated that sbGnIH-2 significantly downregulated key reproductive hormone genes in the brain and pituitary.
Subjects
fish; gonadotropin-releasing hormone (GnRH); gonadotropins; kisspeptins; LPXRFamide; perciforms; reproduction; sea bass
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