Field efficacy of a bioherbicide mimic (DiS-NH2) in a nanoparticle formulation for weed control in durum wheat

Abstract

BACKGROUND: Weed-resistance phenomena have increased dramatically in recent years. Bioherbicides can offer a sustainablealternative to chemical weed control but they often have low water solubility and therefore low efficacy in the field. Theresearch reported here represents the first study on the field efficacy against weeds of a nanoencapsulated bioherbicide mimicof aminophenoxazinones, namely DiS-NH 2 (2,20-disulphanediyldianiline). Field experiments were carried out across three dif-ferent locations to evaluate the bioherbicide disulphide mimic at standard (T1, 0.75 g m−2 ) and double (T2, 1.5 g m−2 ) doseswhen compared to no weed control (NC) and chemical weed controlled (PC) in durum wheat.RESULTS: The nanoencapsulated bioherbicide displayed better soil permeability than the free compound and also showedlower ecotoxicity on comparing the toxic doses on the Caenorhabditis elegans nematode model. It was found that T2 gavethe best performance in terms of phytotoxicity (−57% weed biomass when compared with NC) and crop yield enhancement(3.2 versus 2.2 Mg ha−1 grain yield), while T1 showed comparable results to PC. T1 and T2 did not cause shifts in weed commu-nities and this is consistent with a broad spectrum of phytotoxicity. Moreover, the nanoparticle formulation tested in this studyprovided stable results across all three locations.CONCLUSION: It is reported here for the first time that a nanoencapsulated DiS-NH 2 bioherbicide mimic provided an efficientpost-emergence and contact bioherbicide that can control a wide range of weed species in durum wheat without damagingthe crop. The mimic also has low ecotoxicity and improved soil permeability.© 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.