RT journal article
T1 Hemisynthesis and Absolute Configuration of novel 6-pentyl-2H-pyran- 2-one derivatives from Trichoderma spp
A1 Daoubi, Mourad
A1 Rubio, Belen
A1 Monte, Enrique
A1 Aleu Casatejada, Josefina
A1 González Collado, Isidro
A1 Hermosa, Rosa
A1 Pinedo Rivilla, Cristina
A2 Química Orgánica
K1 trichoderma
K1 pyrone
K1 6-Pentyl-2H-pyran-2-one
K1 trichoderma viride
K1 trichoderma harzianum
K1 secondary metabolites
K1 synthesis
K1 Absolute configuration
K1 Detoxification mechanism
AB A comparative study of the secondary metabolism of two Trichoderma spp. with that of the Thctf1transcription factor gene null mutant of Trichoderma harzianum 34 was carried out in order to deepen ourknowledge of the biosynthetic pathway and mode of action of 6-pentyl-2H-pyran-2-one (1) and itsderivatives as biocontrol agents. New isolated metabolites have shed light on the detoxificationmechanism of 6-pentyl-pyranone by Trichoderma spp. All new compounds were synthesized and theirstereoisomer characterized. The absolute configuration of 6-[(10R,20S)-dihydroxypentyl]-2H-pyran-2-oneand 6-((10S,20R)-20-propyloxiran-1-yl)-2H-pyran-2-one was determined by NMR analysis of the correspondingMosher’s esters.
PB Elsevier
SN 0040-4020
YR 2009
FD 2009-04-18T00:00:00Z
LK http://hdl.handle.net/10498/17357
UL http://hdl.handle.net/10498/17357
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 12-nov-2026