RT journal article T1 Aloe barbadensis: how a miraculous plant becomes reality A1 Chinchilla Salcedo, Nuria A1 Carrera Fernández, Ceferino Adrián A1 García Durán, Alexandra A1 Macías, Mariola A1 Torres Martínez, Ascensión A1 Macías Domínguez, Francisco Antonio A2 Química Orgánica K1 Aloe vera K1 Phytochemistry K1 Acemannan K1 Bioactivity AB Aloe barbadensis Miller is a plant that is native to North and East Africa and has accompanied man for over 5,000 years. The aloe vera plant has been endowed with digestive, dermatological, culinary and cosmetic virtues. On this basis, aloe provides a range of possibilities for fascinating studies from several points of view, including the analysis of chemical composition, the biochemistry involved in various activities and its application in pharmacology, as wellas from horticultural and economic standpoints. The use of aloe vera as a medicinal plant is mentioned in numerous ancient texts such as the Bible. This multitude of medicinal uses has been described and discussed for centuries, thus transforming this miracle plant into reality. A summary of the historical uses, chemical composition and biological activities of this species is presented in this review. The latest clinical studies involved in vivo and in vitro assays conducted with aloe vera gel or its metabolites and the results of these studies are reviewed. PB Phytochem Rev. YR 2013 FD 2013-09 LK http://hdl.handle.net/10498/20273 UL http://hdl.handle.net/10498/20273 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 08-nov-2026