RT journal article
T1 Isolation of Bioactive Compounds from Sunflower Leaves (Helianthus annuus L.) Extracted with Supercritical Carbon Dioxide
A1 El Marsni, Zouhir
A1 Torres Martínez, Ascensión
A1 Varela Montoya, Rosa María
A1 González Molinillo, José María
A1 Casas Cardoso, Lourdes
A1 Mantell Serrano, Casimiro
A1 Martínez de la Ossa Fernández, Enrique José
A1 Macías Domínguez, Francisco Antonio
A2 Química Orgánica
K1 Helianthus annuus L.
K1 Supercritical carbon dioxide
K1 bioactive compounds
K1 sesquiterpene lactones
K1 heliannuol
K1 flavonoids
K1 cytotoxicity and phytoxicity bioassays
AB The work described herein is a continuation of our initial studies on the supercritical fluid extraction (SFE) with CO2 of bioactive substances from Helianthus annuus L. var. Arianna. The selected SFE extract showed high activity in the wheat coleoptile bioassay, in Petri dish phytotoxicity bioassays, and in the hydroponic culture of tomato seeds. Chromatographic fractionations of the extracts and a spectroscopic analysis of the isolated compounds showed 52 substances belonging to 10 different chemical classes, which were mainly sesquiterpene lactones, diterpenes, and flavonoids. Heliannuol M (31), helivypolides K and L (36, 37), and helieudesmanolide B (38) are described for the first time in the literature. Metabolites have been tested in the etiolated wheat coleoptile bioassay with good results in a noteworthy effect on germination. The most active compounds were also tested on tomato seeds, heliannuol A (30) and leptocarpin (45) being the most active, with values similar to those of the commercial herbicide.
PB JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
YR 2015
FD 2015-07
LK http://hdl.handle.net/10498/20316
UL http://hdl.handle.net/10498/20316
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 07-nov-2026