RT journal article
T1 Molecular Docking Study of Conformational Polymorph: Building Block of Crystal Chemistry
A1 Dubey, Rashmi
A1 Kumar Tewari, Ashish
A1 Prakash Singh, Ved
A1 Singh, Praveen
A1 Singh Dangi, Jawahar
A1 Puerta, M. Carmen
A1 Valerga, Pedro
A1 Kant, Rajni
A2 Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica
AB Two conformational polymorphs of novel 2-[2-(3-cyano-4,6-dimethyl-2-oxo-2H-pyridin-1-yl)-ethoxy]-4,6-dimethyl nicotinonitrile have been developed. The crystal structure of both polymorphs (1a and 1b) seems to be stabilized by weak interactions. A difference was observed in the packing of both polymorphs. Polymorph 1b has a better binding affinity with the cyclooxygenase (COX-2) receptor than the standard (Nimesulide).
PB Hindawi
YR 2013
FD 2013
LK http://hdl.handle.net/10498/20430
UL http://hdl.handle.net/10498/20430
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 15-nov-2026