RT journal article
T1 Phytotoxic Activity and Metabolism of Botrytis cinerea and Structure−Activity Relationships of Isocaryolane Derivatives
A1 Ascari, Jociani
A1 Diamantino Boaventura, Maria Amélia
A1 Aparecida Takahashi, Jacqueline
A1 Durán Patrón, Rosa María
A1 Hernández Galán, Rosario
A1 Macías Sánchez, Antonio José
A1 González Collado, Isidro
A2 Química Orgánica
AB Research has been conducted on the biotransformation of (8S,9R)-isocaryolan- 9-ol (4a) and (1S,2S,5R,8S)-8 methylene-1,4,4-trimethyltricyclo[6.2.1.02,5]undecan-12-ol (5a) by the fungal phytopathogen Botrytis cinerea. The biotransformation of compound 4a yielded compounds 6−9, while the biotransformation of compound 5a yielded compounds 10−13. The activity of compounds 4a and 5a against B. cinerea has been evaluated. (8R,9R)- Isocaryolane-8,9-diol (6), a major metabolite of compound 4a, shows activity compared to its parent compound 4a, which is inactive. The effect of isocaryolanes 3, 4a, and 5a, together with their biotransformation products 6−8, 10, and 14−17, on the germination and radicle and shoot growth of Lactuca sativa (lettuce) has also been determined. Compounds 7−13 are described for the first time.
PB Journal of Natural Products
YR 2013
FD 2013-06
LK http://hdl.handle.net/10498/20570
UL http://hdl.handle.net/10498/20570
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 06-nov-2026