RT journal article
T1 Titanium carbenoid-mediated cyclopropanation of allylic alcohols: selectivity and mechanism
A1 Durán Peña, María Jesús
A1 Botubol Ares, José Manuel
A1 R. Hanson, J.
A1 Hernández Galán, Rosario
A1 González Collado, Isidro
A2 Química Orgánica
AB A new method for the chemo- and stereoselective conversion of allylic alcohols into the corresponding cyclopropane derivatives has been developed. The cyclopropanation reaction was carried out with an unprecedentedtitanium carbenoid generated in situ from Nugent’s reagent, manganese and methylene diiodide. The reaction involving the participation of an allylic hydroxyl group, proceeded with conservation of the alkene geometry and in a high diastereomeric excess. The scope, limitations and mechanism of this metal-catalysed reaction are discussed.
PB The Royal Society of Chemistry
YR 2015
FD 2015
LK http://hdl.handle.net/10498/20589
UL http://hdl.handle.net/10498/20589
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 21-sep-2026