RT journal article T1 Assessment of Ultrasound Assisted Extraction as an Alternative Method for the Extraction of Anthocyanins and Total Phenolic Compounds from Maqui Berries (Aristotelia chilensis (Mol.) Stuntz) A1 Vázquez Espinosa, Mercedes A1 Velasco González de Peredo, Ana A1 Ferreiro González, Marta A1 Carrera Fernández, Ceferino Adrián A1 Palma Lovillo, Miguel A1 Fernández Barbero, Gerardo A1 Espada Bellido, Estrella A2 Química Analítica A2 Química Orgánica K1 anthocyanins K1 Aristotelia chilensis (Mol.) Stuntz K1 maqui berry K1 food analysis K1 phenolic compounds K1 superfruit K1 ultrasound assisted extraction AB Research interest regarding maqui (Aristotelia chilensis) has increased over the last yearsdue to its potential health benefits as one of the most antioxidant-rich berries. Ultrasound-assistedextraction (UAE) is an advanced green, fast, and ecological extraction technique for the production ofhigh quality extracts from natural products, so it has been proposed in this work as an ideal alternativeextraction technique for obtaining extracts of high bioactivity from maqui berries. In order todetermine the optimal conditions, the extraction variables (percentage of methanol, pH, temperature,ratio “sample mass/volume of solvent”, amplitude, and cycle) were analyzed by a Box-Behnkendesign, in conjunction with the response surface method. The statistical analysis revealed that thetemperature and the percentage of methanol were the most influential variables on the extractionof the total phenolic compounds and total anthocyanins, respectively. The optimal extraction timewas determined at 15 min for total phenolic compounds, while it was only 5 min for anthocyanins.The developed methods showed a high precision level with a coefficient of variation of less than5%. Finally, the new methods were successfully applied to several real samples. Subsequently, theresults were compared to those that were obtained in previous experiments by means of microwaveassisted extraction (MAE). Similar extraction yields were obtained for phenolic compounds underoptimized conditions. However, UAE proved to be slightly more efficient than MAE in the extractionof anthocyanins. PB MDPI SN 2073-4395 YR 2019 FD 2019-03 LK http://hdl.handle.net/10498/21244 UL http://hdl.handle.net/10498/21244 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 04-nov-2026