RT journal article
T1 Plasma 1α-Hydroxycorticosterone as Biomarker for Acute Stress in Catsharks (Scyliorhinus canicula)
A1 Ruiz Jarabo de la Rocha, Ignacio
A1 Barragan-Mendez, Cristina
A1 Jerez Cepa, Ismael
A1 Fernández-Castro, Miriam
A1 Sobrino, Ignacio
A1 Mancera Romero, Juan Miguel
A1 Aerts, Johan
K1 1a-hydroxycorticosterone
K1 glucocorticoid
K1 Scyliorhinus canicula
K1 shark
K1 stress
AB Glucocorticoids are pleiotropic steroid hormones mediating redistribution of energy.They induce breakdown of glycogen stores and consequent plasma hyperglycaemiaafter stressful situations. Glucocorticoid actions in most vertebrate species areexerted by cortisol and corticosterone. However, 1a-hydroxycorticosterone is thedominant corticosteroid hormone in elasmobranchs, though its effects as aglucocorticoid are unknown. Here we demonstrate, by using ultra-performanceliquid chromatography coupled to tandem mass spectrometry for the quantificationof 1a-hydroxycorticosterone in plasma of the elasmobranch Scyliorhinus canicula,the response of this hormone to an acute-stress situation and for the first timeits glucocorticoid action in elasmobranchs. After an acute air-exposure challenge,S. canicula increased plasma levels of 1a-hydroxycorticosterone altogether withenhanced glycolysis and gluconeogenesis pathways to fuel energy demanding tissues,such as white muscle, during the first hours after the stress situation. We foresee ourstudy as a starting point to evaluate stress responses in elasmobranchs, as well as forfuture applications in the management of these key ecosystem species.
PB FRONTIERS MEDIA SA
SN 1664-042X
YR 2019
FD 2019-09
LK http://hdl.handle.net/10498/21783
UL http://hdl.handle.net/10498/21783
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 08-nov-2026