RT journal article
T1 Effect of Different Insulin Therapies on Obstetric-Fetal Outcomes
A1 López Tinoco, Cristina
A1 Jiménez Blázquez, José Luis
A1 Larrán Escandón, Laura
A1 Roca Rodríguez, María del Mar
A1 Bugatto González, Fernando
A1 Aguilar Diosdado, Manuel
A2 Materno-Infantil y Radiología
A2 Medicina
AB To evaluate the effectiveness of the different insulin therapies on obstetrics-fetal outcomes in womenwith pregestational diabetes mellitus. We enrolled 147 pregnant women with pre-existing type 1 or 2diabetes mellitus. Clinical and biochemical parameters were analysed in relation to obstetric and fetaloutcomes. 14.2% received treatment with Neutral Protamine Hagedorn insulin and short-acting insulinanalogues; 19% with premixed human insulin; 40.1% with insulin glargine and lispro, 6.2% with detemirand aspart and 20% with continuous subcutaneous insulin infusion. All 5 types of treatment achieved areduction of the mean HbA1c during pregnancy (p = 0.01). Pre-pregnancy care was carried out for 48%of patients. We found no statistically significant differences between the different insulin therapiesand the obstetric-fetal outcomes. In conclusión, the different insulin therapies used in patients withpregestational diabetes mellitus does not seem to affect obstetric-fetal outcomes.
PB NATURE PUBLISHING GROUP
SN 2045-2322
YR 2019
FD 2019-11
LK http://hdl.handle.net/10498/21998
UL http://hdl.handle.net/10498/21998
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 11-nov-2026