RT journal article
T1 Microwave-Assisted Extraction of Ricinine from Ricinus communis Leaves
A1 Nebo, Liliane
A1 Varela Montoya, Rosa María
A1 Fernandes, João B.
A1 Palma Lovillo, Miguel
A2 Química Analítica
A2 Química Orgánica
K1 microwave assisted-extraction
K1 ricinine
K1 Ricinus communis
K1 UPLC
K1 response surface methodology
AB The alkaloid ricinine (3-cyano-4-methoxy-N-methyl-2-pyridone) is found in di erent partsof the Ricinus communis plant and is known to possess several bioactive properties, including strongantioxidant activity. In this study, a new microwave-assisted extraction (MAE) method was developedfor the recovery of ricinine from R. communis leaves. The extraction variables studied were extractiontemperature (between 125  C and 175  C), microwave power (between 500Wand 1000 W), extractiontime (between 5 min and 15 min), extraction solvent (between 10% and 90% of EtOAc in MeOH),and solvent-to-sample ratio (between 25:1 mL and 50:1 mL of solvent per gram of the sample).On studying the e ects of extraction variables, both solvent and liquid-to-solid ratio were found toexhibit the highest e ects on ricinine recovery. A fast (15 min) microwave-assisted extraction methodwas developed (high temperatures can be applied because the stability of ricinine is proven in theliterature), allowing for the recovery of ricinine from R. communis leaves. The study revealed thatR. communis leaves had almost 1.5 mg g􀀀1 (dried weight) of ricinine.
PB MDPI
SN 2076-3921
YR 2019
FD 2019-10
LK http://hdl.handle.net/10498/22177
UL http://hdl.handle.net/10498/22177
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 12-nov-2026