RT journal article
T1 Immunotoxicity of polystyrene nanoplastics in different hemocyte subpopulations of Mytilus galloprovincialis
A1 Sendra, Marta
A1 Carrasco-Braganza, María Isabel
A1 Yeste Sigüenza, María del Pilar
A1 Vila, Marta
A1 Blasco, Julian
A2 Ciencia de los Materiales e Ingeniería Metalúrgica y Química Inorgánica
AB Plastic represents 60-80% of litter in the ocean. Degradation of plastic to small fragments leads to the formation of microplastics (MPs <5mm) and nanoplastics (NPs <1 mu m). One of the most widely used and representative plastics found in the ocean is polystyrene (PS). Among marine organisms, the immune system of bivalves is recognized as suitable to assess nanomaterial toxicity. Hemocyte subpopulations [R1 (large granular cells), R2 (small semi-granular cells) and R3 (small agranular or hyaline cells)] of Mytilus galloprovincialis are specialized in particular tasks and functions. The authors propose to examine the effects of different sizes (50 nm, 100 nm and 1 mu m) PS NPs on the different immune cells of mussels when they were exposed to (1 and 10mg.L-1) of PS NPs. The most noteworthy results found in this work are: (i) 1 mu m PS NPs provoked higher immunological responses with respect to 50 and 100nm PS NPs, possibly related to the higher stability in size and shape in hemolymph serum, (ii) the R1 subpopulation was the most affected with respect to R2 and R3 concerning immunological responses and (iii) an increase in the release of toxic radicals, apoptotic signals, tracking of lysosomes and a decrease in phagocytic activity was found in R1.
PB NATURE PUBLISHING GROUP
SN 2045-2322
YR 2020
FD 2020-05
LK http://hdl.handle.net/10498/23700
UL http://hdl.handle.net/10498/23700
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 15-nov-2026