RT journal article
T1 Primary breast cancer and health related quality of life in Spanish women: The EpiGEICAM case-control study
A1 Fernández de Larrea-Baz, Nerea
A1 Pérez-Gómez, Beatriz
A1 Guerrero-Zotano, Ángel
A1 Casas, Ana María
A1 Bermejo, Begoña
A1 Baena Cañada, José Manuel
A1 Antolín, Silvia
A1 Sánchez-Rovira, Pedro
A1 Ramos Vázquez, Manuel
A1 García-Sáenz, José Ángel
A1 Antón, Antonio
A1 Muñoz, Montserrat
A1 de Juan, Ana
A1 Jara, Carlos
A1 Chacón, José Ignacio
A1 Arcusa, Angels
A1 Gil-Gil, Miguel
A1 Adrover, Encarna
A1 Oltra, Amparo
A1 Brunet, Joan
A1 González, Sonia
A1 Bezares, Susana
A1 Lope, Virginia
A1 Martín, Miguel
A1 Pollán, Marina
A2 Medicina
AB This study evaluates the impact of breast cancer (BC) in health related quality of life (HRQL) and in psychological distress (PD) during the initial phases of the disease and looks for contributing factors. A multicentric case-control study, EpiGEICAM, was carried out. Incident BC cases and age- and residence- matched controls were included. Clinical, epidemiological, HRQL (SF-36) and PD information (GHQ-28) was collected. We used multivariable logistic regression models to estimate OR of low HRQL and of PD in cases compared to controls, and to identify factors associated with low HRQL and with PD. Among 896 BC cases and 890 control women, cases had poorer scores than both, the reference population and the control group, in all SF-36 scales. BC women with lower education, younger, active workers, never smokers, those with comorbidities, in stage IV and with surgical treatment had lower physical HRQL; factors associated with low mental HRQL were dissatisfaction with social support, being current smoker and having children. Cases had a fivefold increased odds of PD compared to controls. Managing comorbidities and trying to promote social support, especially in younger and less educated women, could improve well-being of BC patients.
PB NATURE PUBLISHING GROUP
SN 2045-2322
YR 2020
FD 2020-05
LK http://hdl.handle.net/10498/23701
UL http://hdl.handle.net/10498/23701
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 10-may-2026