RT journal article
T1 A novel surgical technique focused on the study of the ileum: The preduodenal ileal transposition
T2 Una nueva técnica quirúrgica focalizada en el estudio del íleon: la transposición preduodenal del íleon
A1 Salas Álvarez, Jesús María
A1 Campos Martínez, Francisco J.
A1 Moreno Arciniegas, Alejandra
A1 Almorza Gomar, David
A1 Pérez Arana, Gonzalo Martín
A1 Prada Oliveira, José Arturo
A1 Camacho Ramírez, Alonso
A2 Anatomía y Embriología Humana
A2 Cirugía
A2 Estadística e Investigación Operativa
K1 Diabetes
K1 Malabsorption syndromes
K1 Metabolic surgery
K1 Incretines
K1 Pancreas
K1 Síndromes malabsortivos
K1 Cirugía metabólica
K1 Incretinas
K1 Páncreas
AB Aims: Our main goal is to study the effects on the carbohydrate metabolism. Thus, we designed various experimental surgical models on healthy non-obese Wistar rats to reproduce several conditions. In this sense, we report a new experimental model. It is well known that bariatric surgery has important effects on the control of Type 2 Diabetes Mellitus. The underlying reasons are yet unknown, although the different theories focused in the release of different hormones after the pass of the nutrients through the tract. These released hormones have opposite effects that come together in a balanced glycemic metabolism.Materials and methods: After bariatric surgical techniques, the modified anatomy resulted in an imbalance of the secreted hormones. Wistar rats were randomized in two groups Sham and surgical group. Our model consisted on the transposition of the terminal ileum right after the pylorus. Weight gain, food intake, and basal glycemia were measured weekly.Results: We did not obtain significant differences between both groups for these functional variables.Conclusions: This technique involved an early pass of the bolus through the ileum. The change on the luminal pH, along with the lack of enzymes to absorb the content, or the changes in the release of several hormones must be variables to the study. The mortality rate was assumable considering it was an experimental model on animals.
PB Publicaciones Permanyer
SN 0009-7411
YR 2020
FD 2020
LK http://hdl.handle.net/10498/23972
UL http://hdl.handle.net/10498/23972
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 08-nov-2026