RT journal article
T1 Optimization and Comparison of Ultrasound and Microwave-Assisted Extraction of Phenolic Compounds from Cotton-Lavender (Santolina chamaecyparissus L.)
A1 Aourach, Mohammed
A1 Velasco González de Peredo, Ana
A1 Vázquez Espinosa, Mercedes
A1 Essalmani, Haiat
A1 Palma Lovillo, Miguel
A1 Fernández Barbero, Gerardo
A2 Química Analítica
K1 cotton-lavender
K1 Santolina chamaecyparissus L
K1 ultrasound-assisted extraction
K1 microwave-assisted extraction
K1 Box-Behnken design
K1 phenolic compounds
K1 UHPLC-QToF-MS
AB The interest in natural phenolic compounds has increased because of their attractive use especially as antioxidant and antimicrobial agents in foods. The large content in phenolic compounds of interest in Santolina chamaecyparissus L. (S. chamaecyparissus) makes this plant a target source that is worthy of note. In this work, new extraction technologies comprising ultrasound (UAE) and microwave (MAE) assisted extraction of the phenolic compounds in S. chamaecyparissus have been developed, optimized, and compared. Several extraction factors have been optimized based on a Box-Behnken design. Such optimized factors include the percentage of methanol in water (25-75%), the temperature (10-70 degrees C), the ultrasound amplitude (20-80%), the ultrasound cycle (0.2-1 s), the solvent pH (2-7) and the solvent-sample ratio (5/0.2-15/0.2 mL/g) with regard to UAE, while the percentage of methanol in water (50-100%), the temperature (50-100 degrees C), the pH (2-7) and the solvent-sample ratio (5/0.2-15/0.2 mL/g) were optimized for MAE. The solvent composition was the most influential parameter both on MAEs (64%) and UAEs (74%). The extraction optimum time was established as 15 min for MAE and 25 min for UAE. Five major phenolic compounds were detected and identified by Ultra-High-Performance Liquid Chromatography-Quadrupole Time of Flight-Mass Spectrometry (UHPLC-QToF-MS) in the extracts: chlorogenic acid, quercetin 3-O-galactoside, quercetin 3-O-glucoside, isoorientin, and cynarin. With the exception of chlorogenic acid, the other four compounds have been identified for the first time in S. chamaecyparissus. The findings have confirmed that MAE is a significantly more efficient extraction method than UAE to extract phenolic compounds from S. chamaecyparissus.
PB MDPI
SN 2073-4395
YR 2021
FD 2021-01
LK http://hdl.handle.net/10498/24518
UL http://hdl.handle.net/10498/24518
LA eng
DS Repositorio Institucional de la Universidad de Cádiz
RD 13-nov-2026