RT journal article T1 Effect of a 12-Week Concurrent Training Intervention on Cardiometabolic Health in Obese Men: A Pilot Study A1 Amaro-Gahete, Francisco J. A1 Ponce González, Jesús Gustavo A1 Corral Pérez, Juan A1 Velázquez Díaz, Daniel A1 Lavie, Carl J. A1 Jiménez Pavón, David A2 Didáctica de la Educación FísicaPlástica y Musical K1 concurrent training K1 cardiac function K1 obesity K1 body composition K1 energy metabolism AB The present study aimed to investigate the effects of a 12-week concurrent training intervention on cardiometabolic health in obese men. Twelve obese men (42.5 +/- 5.3 years old) participated in the current 12-week randomized controlled trial with a parallel group design. The participants were randomly assigned to a concurrent training group or to a no-exercise control group. Anthropometry and body composition assessment were determined by electrical bio-impedance. Blood samples were obtained and a cardiometabolic risk Z-Score was calculated. Energy metabolism-related parameters [i.e., resting metabolic rate (RMR), respiratory quotient (RQ), and substrate oxidation in both resting conditions and during exercise] were determined by indirect calorimetry. Echocardiographic studies were performed using an ultrasound system equipped with a transducer to measure cardiac function. A significant decrease of weight (Delta = -4.21 kg; i.e., primary outcome), body mass index (Delta = -1.32 kg/m(2)), fat mass (FM; Delta = -3.27 kg), blood pressure (BP; Delta = -10.81 mmHg), and cardiometabolic risk Z-Score (Delta = -0.39) was observed in the exercise group compared with the control group (all P < 0.05), while no significant changes were noted in waist circumference (WC), lean mass (LM), bone mineral content, glycemic and lipid profiles, liver function, nor in energy metabolism-related parameters (all P > 0.1). Moreover, a significant increment of left ventricular (LV) end diastolic diameter (Delta = -4.35 mm) was observed in the exercise group compared with the control group (P = 0.02). A 12-week concurrent training intervention is an effective strategy to induce weight and fat loss with simultaneous reductions of BP and cardiometabolic risk, and improving cardiac function in obese men. PB FRONTIERS MEDIA SA SN 1664-042X YR 2021 FD 2021-02 LK http://hdl.handle.net/10498/24692 UL http://hdl.handle.net/10498/24692 LA eng NO LCurrent research activities of DJ-P are supported by a grant from the Spanish Ministry of Science and Innovation-MINECO (RYC-2014-16938) and the Spanish Ministry of Economy and Competitiveness-MINECO/FEDER (DEP2016-76123R), the Government of Andalusian, Integrated Territorial Initiative 2014-2020 for the province of Cadiz (PI-00022017); the European Union's ERASMUS C SPORT program (Grant Agreement: 603121-EPP-1-2018-1-ES-SPO-SCP), and the EXERNET Research Network on Exercise and Health in Special Populations (DEP2005-00046/ACTI). Technology Fund-FEDER funds (R&D&I Operating Program) by and for the benefit of companies (Technology Fund) INNTERCONECTA (BRISA Contract-University of Cadiz). The results of the study are presented clearly, honestly, and without fabrication, falsification, or inappropriate data manipulation. DS Repositorio Institucional de la Universidad de Cádiz RD 08-nov-2026