RT journal article T1 Effects of intracoronary antithrombotics on ventricular function: A comparison of tenecteplase versus abciximab during primary percutaneous intervention in myocardial infarction A1 Morales-Ponce, Francisco J. A1 González Pérez, Pablo José A1 Blasco-Turrión, Sara A1 Sánchez-Brotons, Juan Antonio A1 Collado-Moreno, Carmen A1 Martínez-Romero, Pedro A1 Martínez-Morentín, Eduardo A1 Caro-Mateo, Pilar A2 Medicina AB Adjunctive medical therapy during primarypercutaneous coronary intervention (PPCI) isbased on anticoagulation and antiplatelet drugs. Additionally,the glycoprotein IIb/IIIa inhibitor (GPI)abciximab has been shown to reduce infarct size insome clinical trials [1]. However, the role of intracoronaryfibrinolysis has not been well establishedduring PPCI. We sought to explore the hypothesisthat a locally administered fibrinolytic could bemore effective in dissolving coronary thrombusat the macro and microvasculature than addinga third antiplatelet drug in patients already receivingdouble antiplatelet therapy, and therefore improvemyocardial perfusion and left ventricular function. PB VIA MEDICA SN 1897-5593 YR 2021 FD 2021-01 LK http://hdl.handle.net/10498/24794 UL http://hdl.handle.net/10498/24794 LA eng DS Repositorio Institucional de la Universidad de Cádiz RD 10-nov-2026